# What validity tests must laboratories conduct on primary oral fluid specimens?

**Citation:** 49 CFR 40.93  
**Type / status:** regulation / current  
**Agency:** Pipeline and Hazardous Materials Safety Administration  
**Effective:** 2026-08-18  
**Published:** Not stated

As a laboratory, if you conduct validity testing under § 40.92, you must conduct it in accordance with the requirements of this section.

(a) You may test for a biomarker such as albumin or immunoglobulin G (IgG) or a test for a specific adulterant.

(b) You must follow the applicable HHS requiremen

## Document text

As a laboratory, if you conduct validity testing under § 40.92, you must conduct it in accordance with the requirements of this section.

(a) You may test for a biomarker such as albumin or immunoglobulin G (IgG) or a test for a specific adulterant.

(b) You must follow the applicable HHS requirements for any additional validity testing.

[88 FR 27643, May 2, 2023]

## Provenance

- Official: Yes
- Source: <https://www.ecfr.gov/on/2026-08-18/title-49/section-40.93>
- Source ID: `ecfr`
- SHA-256: `3b0fa57a433dfddc768aec1882ef42795aa7b27bae89864ad938b620df321d24`
- Retrieved: 2026-08-20T05:54:21.729Z
- Exported: 2026-08-23T21:36:48.222Z
- Document slug: `49-cfr-40-93`

### Source metadata

```json
{
  "cfrTitle": 49,
  "part": "40",
  "section": "40.93",
  "subpart": "Subpart F—Drug Testing Laboratories",
  "corpusVersion": "2026-08-18",
  "jurisdiction": "US"
}
```