# Dangerous Goods SME — Hazardous Materials Safety Interpretation **Citation:** 19-0133 **Type / status:** guidance / guidance **Agency:** Pipeline and Hazardous Materials Safety Administration **Effective:** Not stated **Published:** 2020-04-28 19-0133 response to Dangerous Goods SME concerning 172.203. ## Document text <<>> U.S. Department of Transportation Pipeline and Hazardous Materials Safety Administration 1200 New Jersey Avenue, SE Washington, DC 20590 William Canterbury Dangerous Goods SME AlbemarleCongress Street Suite 900 Charlotte, NC 28209 April 28, 2020 Reference No. 19-0133 Dear Mr. Canterbury: This letter is in response to your December 12, 2019, email requesting clarification of the Hazardous Materials Regulations (HMR; 49 CFR Parts 171-180) applicable to the proper shipping name for a compound containing a mixture of hydrocarbons. You state that the safety data sheet (SDS) you included in your email lists the technical names as “(Lithium Diisopropylamide, Heptane (C7 hydrocarbon mixture)).” Specifically, you ask whether the words “C7 hydrocarbon mixture” must appear as a part of the hazmat shipping description on the shipping paper. The answer is no. The addition of “C7 hydrocarbon mixture” is not required because it is redundant with the listed technical name Heptane. Note that technical names must be included in parentheses with the hazardous material shipping description and generally, at least two components which most predominantly contribute to the hazard(s) of the mixture or solution must be entered on the shipping paper. See § 172.203(k). I hope this information is helpful. Please contact us if we can be of further assistance. Sincerely, Dirk Der Kinderen Chief, Standards Development Branch Standards and Rulemaking Division <<>> January, Ikeya CTR (PHMSA) Casey -19-0133 From: INFOCNTR (PHMSA) Sent: To: Hazmat Interps Thursday, December 12, 2019 2:28 PM Subject: FW: Hazmat Interpretation request - Technical name for UN 2924 Flammable liquids, corrosive, n.o.s Attachments: SDS SKU 10000280.PDF; Canterbury_LOl.docx Hello Alice and ikeya, Please see below for interpretation request, as well as attached notes document. Please contact our office with any questions. Thank you, Kathryn, HMIC From: William Canterbury [mailto:william.canterbury@albemarle.com] Sent: Thursday, December 12, 2019 11:20 AM To: INFOCNTR (PHMSA) Subject: Hazmat Interpretation request - Technical name for UN 2924 Flammable liquids, corrosive, n.o.s DOT / PHMSA Team We have a difference of opinion within our team here at Albemarle as to how to list the technical name for this compound and respectively submit this request for your advice. The attached SDS list the technical name as (Lithium diisopropylamide, Heptane(C7 hydrocarbon mixture)) Another option being considered is (Tetrahydrofuran, Lithium Diisopropylamide, Heptane) Please let me know if you need any additional information and note my contact info and mailing address are below. Thank you and have a great day! Just some notes for my personal ref 49 CFR 171.8 Technical name means a recognized chemical name or microbiological name currently used in scientific and they readily identify the general chemical group, or microbiological group. Examples of acceptable generic chemical technical handbooks, journals, and texts. Generic descriptions are authorized for use as technical names provided descriptions are organic phosphate compounds, petroleum aliphatic hydrocarbons and tertiary amines. For proficiency testing only, generic microbiological descriptions such as bacteria, mycobacteria, fungus, and viral samples may be used. Except for names which appear in subpart B of part 172 of this subchapter, trade names may not be used as technical names. 172.203 (K)(1) 1 <<>> at least two components most predominately contributing to the hazards of the mixture or solution must be entered (1) If a hazardous material is a mixture or solution of two or more hazardous materials, the technical names of on the shipping paper as required by paragraph (k) of this section. For example, "UN 2924, Flammable liquid, corrosive, n.o.s., 3 (8), II (contains Methanol, Potassium hydroxide)". William Canterbury | I ALBEMARLE | Dangerous Goods SME, US DOT PHMSA, IATA, IMO/IMDG Certified 4250 Congress Street, Suite 900, Charlotte NC 28209 | 2: Office: 704-417-0135| 2: Cell: 704-287-7177 | X: William.canterbury@albemarle.com <<>> Hello Alice and Ikeya, The requester spoke with Lynsey in the HMIC. She pointed him to the guidance in 172.101(c)(10) about using the two components most predominantly contributing to the hazard and that it is the shipper's responsibility to properly classify. He insisted on moving forward with a LOl. After looking at his LOI, I gave him a call to clarify exactly what his question was and to provide him with letters 14-0244 and 03- 0189 essentially, he still wants to verify his letter but I got a better idea for what he is looking for. In the request, he lists the two options for technical names, his main question is on the inclusion of "C7 hydrocarbon mixture" after heptane. The SDS places it after the heptane in section 14 but he is unsure if he is required to include that because C7 hydrocarbon mixture is basically synonymous with heptane. Please contact our office with any questions. Thank you, Kathryn, HMIC <<>> SAFETY DATA SHEET I ALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: SECTION 1. IDENTIFICATION Product name : Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene Manufacturer or supplier's details Company name of supplier : Albemarle Corporation Address : 4250 Congress Street, Suite 900 United States of America (USA) , NC 28209 Telephone : 980.299.5700 Telefax : 980.299.5512 Emergency telephone : +32 (0) 70-233-201 (EUROPE) (+1)225-344-7147 (US and WORLDWIDE) +65-6733-1661 (ASIA PACIFIC) +86-532-8388-9090 (CHINA) +61 2 8014 4558 or 18000 74234 (Australia) Contact person product safe- : DEPARTMENT OF PRODUCT SAFETY E-mail address : PRODUCTSAFETY@ALBEMARLE.COM Recommended use of the chemical and restrictions on use Recommended use : Reagent for organic synthesis. Transported isolated intermediate Restrictions on use Use only in closed systems. SECTION 2. HAZARDS IDENTIFICATION GHS classification in accordance with 29 CFR 1910.1200 Flammable liquids : Category 2 Skin corrosion : Category 1A Serious eye damage : Category 1 1/29 <<>> SAFETY DATA SHEET I ALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: Carcinogenicity : Category 2 systemic toxicity - single Specific target organ Category 3 (Respiratory system, Central nervous system) exposure Specific target organ systemic toxicity - repeated : Category 2 exposure Aspiration hazard Category 1 Acute aquatic toxicity Category 2 Chronic aquatic toxicity : Category 2 GHS label elements Hazard pictograms : ! ·2 Signal Word : Danger Hazard Statements : H225 Highly flammable liquid and vapor. H314 Causes severe skin burns and eye damage. H304 May be fatal if swallowed and enters airways. H335 May cause respiratory irritation. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. repeated exposure. H373 May cause damage to organs through prolonged or H411 Toxic to aquatic life with long lasting effects. Precautionary Statements : Prevention: P202 Do not handle until all safety precautions have been read P201 Obtain special instructions before use. and understood. P210 Keep away from heat/sparks/open flames/hot surfaces. No smoking. P240 Ground/bond container and receiving equipment. P233 Keep container tightly closed. P241 Use explosion-proof electrical/ ventilating/ lighting/ equip- ment. P242 Use only non-sparking tools. P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P243 Take precautionary measures against static discharge. 2/29 <<>> SAFETY DATA SHEET I ALBEMARLE according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: P264 Wash skin thoroughly after handling. 271 Use only outdoors or in a well-ventilated area 273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. Response: P301 + P310 IF SWALLOWED: Immediately call a POISON P301 + P330 + P331 IF SWALLOWED: Rinse mouth. Do NOT CENTER/doctor. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately induce vomiting. P304 + P340 + P310 IF INHALED: Remove person to fresh air all contaminated clothing. Rinse skin with water/shower. CENTER/doctor. and keep comfortable for breathing. Immediately call a POISON water for several minutes. Remove contact lenses, if present P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with CENTER/doctor. and easy to do. Continue rinsing. Immediately call a POISON attention. P308 + P313 IF exposed or concerned: Get medical advice/ P378 In case of fire, use extinguish media on basis of NaCl or pulverized limestone. Never use water. Storage: tightly closed P403 + P233 Store in a well-ventilated place. Keep container P403 + P235 Store in a well-ventilated place. Keep cool. P405 Store locked up. Disposal: P501 Dispose of contents/ container to an approved waste dis- posal plant. Other hazards The information required is contained in this Material Safety Data Sheet. SECTION 3. COMPOSITION/INFORMATION ON INGREDIENTS Substance / Mixture : Mixture Chemical nature : Organoamide Hazardous ingredients Chemical name Naphtha (petroleum), hydrotreated light CAS-No. 64742-49-0 Concentration (% w/w) >= 30 - < 50 (Heptane (C7 hydrocarbon mixture)) 3/29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: lithium disopropylamide |4111-54-0 >= 20 - < 30 tetrahydrofuran 109-99-9 >= 20 - < 30 diisopropylamine 100-41-4 >= 10 - < 20 1108-18-9 >= 3-<5 * Note: The exact concentrations of the above listed chemicals are being withheld as a trade se- cret. SECTION 4. FIRST AID MEASURES General advice : First Aid responders should pay attention to self-protection Move out of dangerous area. and use the recommended protective clothing Take off contaminated clothing and shoes immediately. Keep warm and in a quiet place. If inhaled : Move to fresh air. If not breathing, give artificial respiration. Call a physician immediately. Keep the victim calm and in a semi-upright position. In case of skin contact : Wash off immediately with plenty of water for at least 15 minutes. Call a physician immediately. In case of eye contact : Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Call a physician immediately. If swallowed : Clean mouth with water and drink afterwards plenty of water. Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Call a physician immediately. Most important symptoms and effects, both acute and : Headache delayed Nausea Vomiting Tiredness Drowsiness Dizziness Unconsciousness Risk of serious damage to the lungs (by aspiration). If ingested, severe burns of the mouth and throat, as well as a Risk of product entering the lungs on vomiting after ingestion. danger of perforation of the esophagus and the stomach. Notes to physician : Treat symptomatically. For specialist advice physicians should contact the Poisons Information Service. 4/29 <<>> SAFETY DATA SHEET MALBEMARLE™ 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 SECTION 5. FIRE-FIGHTING MEASURES Suitable extinguishing media : Dry extinguishing media based on NaCl or pulverized limestone. Unsuitable extinguishing media : Water Foam Carbon dioxide (CO2) fighting Specific hazards during fire : Vapors may form explosive mixtures with air. Vapors are heavier than air and may spread along floors. Flash back possible over considerable distance. Hazardous decomposition products formed under fire conditions. ucts Hazardous combustion prod- : Carbon monoxide Carbon dioxide (CO2) Further information : Use a water spray to cool fully closed containers. Be aware of a dangerous reaction with water, if the container is ruptured. Collect contaminated fire extinguishing water separately. This must not be discharged into drains. be disposed of in accordance with local regulations. Fire residues and contaminated fire extinguishing water must Special protective equipment: Wear full protective clothing and self-contained breathing for fire-fighters apparatus. SECTION 6. ACCIDENTAL RELEASE MEASURES tive equipment and emer- Personal precautions, protec- : Remove all sources of ignition. gency procedures Ensure adequate ventilation. Avoid contact with skin, eyes and clothing. Wear personal protective equipment. Keep people away from and upwind of spill/leak. Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. Environmental precautions : Do not flush into surface water or sanitary sewer system. Avoid subsoil penetration. Methods and materials for : Do not allow contact with water. containment and cleaning up Cover spilled material with limestone powder. Pick up and transfer to properly labeled containers. Non-sparking tools should be used. Adequate disposal 5 / 29 <<>> SAFETY DATA SHEET M ALBEMARLE 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Print Date: Date of first issue: 03/04/2019 12/09/2019 SECTION 7. HANDLING AND STORAGE Advice on protection against: Vapors may form explosive mixtures with air. fire and explosion Flash back possible over considerable distance. Vapors are heavier than air and may spread along floors. Use only explosion-proof equipment. Take precautionary measures against static discharge. Keep away from open flames, hot surfaces and sources of Uncleaned empty containers can contain product gases, ignition. which form explosive mixtures with air. Advice on safe handling : Handle under inert gas. Protect from moisture. Use product only in closed system. Provide exhaust ventilation close to floor level. Provide sufficient air exchange and/or exhaust in work rooms. Avoid formation of aerosol. Handle in accordance with good industrial hygiene and safety Wear personal protective equipment. in general, emissions are controlled and prevented by practice. implementing an appropriate management system, including regular informing and training workers. Conditions for safe storage : Keep under inert gas. ventilated place. Keep containers tightly closed in a dry, cool and well- Keep away from heat. Keep away from direct sunlight. Protect from moisture. Do not allow contact with air. Protect from frost. Materials to avoid : Never allow product to get in contact with water during storage. Incompatible with oxidizing agents. Do not store near acids. Further information on stor-: Keep at temperatures between 0°C and 15°C. age stability SECTION 8. EXPOSURE CONTROLS/PERSONAL PROTECTION Ingredients with workplace control parameters Ingredients CAS-No. | Value type Control parame- (Form of ters / Permissible Basis 6/29 <<>> SAFETY DATA SHEET according to OSHA Hazard Communication Standard 29CFR I ALBEMARLE® 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of first issue: 03/04/2019 Date of last issue: 03/04/2019 Print Date: 12/09/2019 Naphtha (petroleum), (C7 hydrocarbon mixture)) hydrotreated light (Heptane 64742-49-0 exposure) concentration TWA 2,000 mg/m3 500 ppm OSHA Z-1 TWA 400 ppm OSHA PO 1,600 mg/m3 tetrahydrofuran 109-99-9 TWA STEL 50 ppm ACGIH ST 100 ppm ACGIH 250 ppm NIOSH REL TWA 735 mg/m3 200 ppm NIOSH REL TWA 590 mg/m3 200 ppm OSHA Z-1 TWA 590 mg/m3 590 mg/m3 200 ppm OSHA PO STEL 250 ppm OSHA PO ethylbenzene 100-41-4 735 mg/m3 TWA TWA 20 ppm ACGIHR 100 ppm NIOSH REL ST 435 mg/m3 545 mg/m3 125 ppm NIOSH REL TWA 435 mg/m3 100 ppm OSHA Z-1 TWA 100 ppm OSHA PO STEL 435 mg/m3 545 mg/m3 125 ppm OSHA PO diisopropylamine 108-18-9 TWA TWA 5 ppm ACGIHR 20 mg/m3 5 ppm NIOSH REL TWA 5 ppm 20 mg/m3 OSHA Z-1 TWA 20 mg/m3 5 ppm OSHA PO Biological occupational exposure limits [Ingredients CAS-NO. Control Biological TSam- [Permissible Basis parameters specimen pling time concentra- tetrahydrofuran 109-99-9 Tetrahydrof Urine End of tion uran shift (As 2 mg/l ACGIH soon as BEI possible exposure after 7/29 <<>> SAFETY DATA SHEET Il ALBEMARLE according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 ethylbenzene 100-41-4 Sum of (ceases) mandelic Urine shift (As End of 0.15 g/g ACGIH creatinine BEI acid and soon as phenyl, possible glyoxylic acid Exposure after ceases) Engineering measures : Use product only in closed system. rooms. Provide sufficient air exchange and/or exhaust in work Provide exhaust ventilation close to floor level. Take precautionary measures against static discharge. standard. Electrical equipment should be protected to the appropriate Personal protective equipment Respiratory protection : In case of inadequate ventilation wear respiratory protection. ABEK-P2-filter Recommended Filter type: When prolonged exposure is expected: Wear full protective clothing and self-contained breathing apparatus. Hand protection Material : Wear suitable gloves. Material : Flame retardant gloves Remarks : Protective gloves and Protective gloves against thermal risks The choice of an appropriate glove does not only depend on its material but also on other quality features and is different from one producer to the other. The exact break through time can be obtained from the protective glove producer and this has to be observed. Protective gloves have to be replaced at the first sign of deterioration. Eye protection : Tightly fitting safety goggles Face-shield Skin and body protection : Flame retardant antistatic protective clothing. Complete suit protecting against chemicals Protective measures : Handle in accordance with good industrial hygiene and safety practice. 8/29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 Ensure that eye flushing systems and safety showers are located close to the working place. Hygiene measures : Take off contaminated clothing and shoes immediately. Avoid contact with skin, eyes and clothing. Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. Smoking, eating and drinking should be prohibited in the Keep away from food, drink and animal feedingstuffs. Wash hands before breaks and at the end of workday. SECTION 9. PHYSICAL AND CHEMICAL PROPERTIES Appearance : liquid Color : slight, yellow, to, red brown Odor : solvent Odor Threshold No data available рн : alkaline Crystallization temperature : < 32 °F/ < 0°C Boiling point/boiling range : 151 °F / 66 °C Tetrahydrofuran Flash point : -6.2 °F/ -21.2 °C (1,013 hPa) Method: closed cup Tetrahydrofuran Evaporation rate : No data available Flammability (solid, gas) : No data available Flammability (liquids) : Flammability (liquids) Remarks: Highly flammable liquid and vapor. Self-ignition : not auto-flammable flammability limit Upper explosion limit / Upper : 12 %(V) Tetrahydrofuran Lower explosion limit / Lower: 1.5 %(V) flammability limit Tetrahydrofuran 9/29 <<>> SAFETY DATA SHEET MALBEMARLE™ according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 Vapor pressure : No data available Relative vapor density : No data available Relative density : No data available Density : ca. 0.80 g/cm3 (68 °F / 20 °C) Solubility(ies) Water solubility : Not applicable, Reacts violently with water. Solubility in other solvents : No data available octanol/water Partition coefficient: n- : No data available Autoignition temperature 419 °F / 215 °C Heptane Decomposition temperature > 104 °F / > 40 °C To avoid thermal decomposition, do not overheat. Viscosity, dynamic : No data available Viscosity, kinematic No data available Explosive properties : Vapors may form explosive mixtures with air. SECTION 10. STABILITY AND REACTIVITY Reactivity : Risk of violent reaction. Chemical stability : Sensitive to air. Decomposes on heating. •ated by heating Decomposition under influence of moisture is highly acceler- Possibility of hazardous reac- : Reacts violently with water. tions May form explosive peroxides. Vapors may form explosive mixture with air. Conditions to avoid : Keep away from open flames, hot surfaces and sources of ignition. Protect from moisture. Do not allow contact with air. Take action to prevent static discharges. Protect from frost, heat and sunlight. 10 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: Incompatible materials : Water Acids Oxidizing agents Hazardous decomposition products : Decomposes in contact with water. Lithium hydroxide Disopropylamine SECTION 11. TOXICOLOGICAL INFORMATION Acute toxicity Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (CZ hydrocarbon mixture)): Acute oral toxicity : LD50 (Rat): > 5,840 mg/kg Method: OECD Test Guideline 401 Test substance: Read-across (Analogy) Acute inhalation toxicity : LC50 (Rat): > 23.3 mg/l Exposure time: 4 h Method: OECD Test Guideline 403 Test atmosphere: vapor GLP: yes Test substance: Read-across (Analogy) Acute dermal toxicity : LD50 (Rat): > 2,800 mg/kg Method: OECD Test Guideline 402 Test substance: Read-across (Analogy) tetrahydrofuran: Acute oral toxicity : LD50 (Rat, male and female): 1,650 mg/kg Acute inhalation toxicity : LC50 (Rat, male and female): > 14.7 mg/l Exposure time: 6 h Test atmosphere: vapor literature. Remarks: Information taken from reference works and the Acute dermal toxicity : LD50 (Rat, male and female): > 2,000 mg/kg GLP: yes Method: OECD Test Guideline 402 Remarks: Limit Test ethylbenzene: Acute oral toxicity : LD50 (Rat): 3,500 mg/kg 11 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lehtame Etsyronzymide abt. 27% in THFI SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: Acute inhalation toxicity : LC50 (Rat): 17.2 mg/l Test atmosphere: vapor Exposure time: 4 h Acute dermal toxicity : LD50 (Rabbit): 15,354 mg/kg diisopropylamine: Acute oral toxicity : LD50 (Rat, male and female): 420 mg/kg Method: US EPA Test Guideline OPP 81-1 Acute inhalation toxicity : LC50 (Rat, male and female): 5.35 mg/l Exposure time: 4 h Test atmosphere: vapor Method: OECD Test Guideline 403 Skin corrosion/irritation Product: Remarks : Causes severe burns. Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Species Method Exposure time CEcO Test Guideline 40s Test substance Result : Skin irritation : Read-across (Analogy) lithium disopropylamide: Result : Causes severe burns. tetrahydrofuran: Species Exposure time Rabbit 72 h Result Method : Draize Testation Draize Test diisopropylamine: Species Method Exposure time Result OECD Test Guideline 404 Causes severe burns. 12/29 <<>> SAFETY DATA SHEET MALBEMARLE according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THFI Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 GLP : yes Serious eye damage/eye irritation Product: Remarks : Causes serious eye damage. Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Species Result : Rabbit Test substance : Read-across (Analogy) No eye irritation lithium diisopropylamide: Result : Risk of serious damage to eyes. tetrahydrofuran: Result Remarks Intaring ton taes Information taken from reference works and the literature. disopropylamine: Species Exposure time Result :Rabbit Irreversible effects on the eye Method DECD Test Guideline 405 Respiratory or skin sensitization Product: Remarks : No data available Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Test Type Routes of exposure Maximization Test Species Skin contact Method Guinea pig Result OECD Test Guideline 406 Test substance Did not cause sensitization on laboratory animals. 13 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 tetrahydrofuran: Test Type Method Species Local lymph node assay (LLNA) Mouse Result GLP diisopropylamine: Test Type Routes of exposure Main contion Test Skin contact Species Method OECD Test Guideline 406 Guinea pig GLP Result Does not cause skin sensitization. Germ cell mutagenicity Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Genotoxicity in vitro : Test Type: reverse mutation assay Test system: Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Test substance: Read-across (Analogy) Test Type: reverse mutation assay Test system: Escherichia coli Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative Test substance: Read-across (Analogy) tetrahydrofuran: Genotoxicity in vitro : Test Type: In vitro mammalian cell gene mutation test Metabolic activation: with and without metabolic activation Test system: Chinese hamster ovary cells Result: negative Method: OECD Test Guideline 476 GLP: yes Test Type: reverse mutation assay Test system: Salmonella typhimurium Metabolic activation: with and without metabolic activation Method: OECD Test Guideline 471 Result: negative 14/29 <<>> SAFETY DATA SHEET MALBEMARLE according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 GLP: yes Genotoxicity in vivo : Test Type: In vivo micronucleus test Species: Mouse (male and female) Strain: B6C3F1 Application Route: inhalation (vapor) Method: OECD Test Guideline 474 Result: negative ethylbenzene: Genotoxicity in vitro : Test Type: In vitro Mammalian Cell Gene Mutation Test Test system: mouse lymphoma cells Method: OECD Test Guideline 476 Result: negative Test Type: Ames test Method: OECD Test Guideline 471 Test system: Salmonella typhimurium Result: negative Genotoxicity in vivo : Species: Mouse (male and female) Application Route: Inhalation Method: OECD Test Guideline 474 Result: negative diisopropylamine: Genotoxicity in vitro : Test Type: reverse mutation assay Metabolic activation: with and without metabolic activation Test system: Salmonella typhimurium Result: negative Method: OECD Test Guideline 471 GLP: yes Carcinogenicity Ingredients: tetrahydrofuran: Application Route Species inhalation (vapor) Exposure time rean adorate Group 2 Years NOAEC Frequency of Treatment GLP Carcinogenicity - Assess- : Limited evidence of carcinogenicity in animal studies 15 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: ment IARC 109-99-9 Group 2B: Possibly carcinogenic to humans Not Assigned 004128; Possibly carcinogenic to humans Not Assigned OSHA No component of this product present at levels greater than or equal to 0.1% is on OSHA's list of regulated carcinogens. NTP identified as a known or anticipated carcinogen by NTP. No ingredient of this product present at levels greater than or equal to 0.1% is Reproductive toxicity Ingredients: tetrahydrofuran: Effects on fertility : Test Type: Two-generation study Strain: wistar Species: Rat, male and female Application Route: Oral General Toxicity F1: NOAEL: 305 mg/kg body weight General Toxicity Parent: NOAEL: 305 mg/kg bw/day Method; OECD Test Guideline 416 Fertility: NOAEL: 782 mg/kg bw/day GLP: yes Effects on fetal development : Test Type: Pre-natal Species: Rat Strain: Sprague-Dawley Application Route: inhalation (vapor) General Toxicity Maternal: NOAEL: 1,800 ppm Frequency of Treatment: 7 days/week Method: OECD Test Guideline 414 Developmental Toxicity: NOAEL: 1,800 ppm Result: Animal testing did not show any effects on fetal development. GLP: yes STOT-single exposure Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Assessment Routes of exposure The suion The substance or mixture is classified as specific target organ toxicant, single exposure, category 3 with narcotic effects. 16 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THFI Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of first issue: 03/04/2019 Date of last issue: 03/04/2019 Print Date: 12/09/2019 tetrahydrofuran: Routes of exposure Assessment The suit. The substance or mixture is classified as specific target organ toxicant, single exposure, category 3 with respiratory tract irritation. diisopropylamine: Assessment : The substance or mixture is classified as specific target organ irritation., May cause respiratory irritation. toxicant, single exposure, category 3 with respiratory tract STOT-repeated exposure Ingredients: ethylbenzene: Assessment : The substance or mixture is classified as specific target organ toxicant, repeated exposure, category 2. Repeated dose toxicity Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): NOAEL Species Rat, male and femal Method Exposure time Test atmosphere Application Route 12.35 mg/ Inhalation vapor 90 d Test substance OECD Test Guideline 413 Read-across (Analogy) tetrahydrofuran: NOAEL Species Rat, male and female Exposure time Application Route 1,000 mg/l Oral Method Group 28 d OECD Test Guideline 407 yes NOAEC Species Rat, male and female Test atmosphere Application Route Inhalation 1800 ppm Exposure time 90 d vapor 17/29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Print Date: Date of first issue: 03/04/2019 12/09/2019 Group Method GLP Sub-chronic toxicity study (90-day) ethylbenzene: Species LOAEL NOAEL : Rat, male and female 75 mg/kg Application Route 250 mg/kg Method Exposure time 90 d Oral OECD Test Guideline 408 diisopropylamine: Species NOAEL Exposure time Application Route 50 mg/kg bw/day Oral Method 33 d : Regulation (EC) No. 440/2008, Annex, B.7 Species NOAEL : Rat, male and female Exposure time Application Route >150 mg/kg bw/day Skin contact Method Number of exposures 5 d/wk 28 d GLP OECD Test Guideline 410 : yes Aspiration toxicity Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): garded as if it causes a human aspiration toxicity hazard. The substance or mixture is known to cause human aspiration toxicity hazards or has to be re- ethylbenzene: garded as if it causes a human aspiration toxicity hazard. The substance or mixture is known to cause human aspiration toxicity hazards or has to be re- Further information Product: Remarks : If ingested, severe burns of the mouth and throat, as well as a danger of perforation of the esophagus and the stomach. Evaporation of solvents may cause irritation to eyes and mu- 18/29 <<>> SAFETY DATA SHEET MALBEMARIE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 Inhalation of high vapor concentrations may cause symptoms cous membranes. like headache, dizziness, tiredness, nausea and vomiting. SECTION 12. ECOLOGICAL INFORMATION Ecotoxicity Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Toxicity to fish : LL50 (Oncorhynchus mykiss (rainbow trout)): > 13.4 mg/l End point: mortality Test Type: semi-static test Exposure time: 96 h Method: OECD Test Guideline 203 Toxicity to daphnia and other : EL50 (Daphnia magna (Water flea)): 3 mg/l aquatic invertebrates Exposure time: 48 h End point: Immobilization Test substance: Read-across (Analogy) Test Type: static test Method: OECD Test Guideline 202 GLP: yes Toxicity to algae : EL50 (Pseudokirchneriella subcapitata (green algae)): 10 mg/l Exposure time: 72 h End point: Growth rate Test Type: static test Test substance: Read-across (Analogy) Method: OECD Test Guideline 201 GLP: yes Toxicity to daphnia and other : NOEC (Daphnia magna (Water flea)): 0.017 mg/l ic toxicity) aquatic invertebrates (Chron- Exposure time: 21 d Test Type: static test Analytical monitoring: yes Test substance: Read-across (Analogy) GLP: yes Method: OECD Test Guideline 211 Toxicity to microorganisms : EL50 (Tetrahymena pyriformis): 26.8 mg/l Exposure time: 48 h End point: Growth rate Method: QSAR GLP: 19/29 <<>> SAFETY DATA SHEET I ALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 tetrahydrofuran: Toxicity to fish : LC50 (Pimephales promelas (fathead minnow): 2, 160 mg/l Exposure time: 96 h End point: mortality Test Type: flow-through test Analytical monitoring: yes Method: OECD Test Guideline 203 Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 3,485 mg/l aquatic invertebrates End point: mortality Test Type: static test Exposure time: 48 h Method: OECD Test Guideline 202 Toxicity to algae : TTC (Scenedesmus quadricauda (Green algae)): 3,700 mg/l End point: Growth rate Test Type: static test Exposure time: 8 d Remarks: Information taken from reference works and the literature. icity) Toxicity to fish (Chronic tox- : NOEC (Pimephales promelas (fathead minnow)): 216 mg/l Exposure time: 33 d End point: Growth inhibition Analytical monitoring: yes Test Type: flow-through test literature. Remarks: Information taken from reference works and the Toxicity to microorganisms : IC50 (activated sludge): 460 mg/l End point: Respiration inhibition Exposure time: 3 h Test Type: static test Method: OECD Test Guideline 209 ethylbenzene: Toxicity to algae : IC50 (Selenastrum capricornutum (green algae)): 4.6 mg/l Method: OECD Test Guideline 201 Toxicity to microorganisms : EC50 (Photobacterium phosphoreum): 9.68 mg/l Exposure time: 30 min diisopropylamine: Toxicity to fish : LC50 (Leuciscus idus (Golden orfe)): 26 mg/l End point: mortality Test Type: static test Exposure time: 96 h 20 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 Method: DIN 38412 Toxicity to daphnia and other : LC50 (Daphnia magna (Water flea)): 110 mg/l aquatic invertebrates End point: Immobilization Exposure time: 48 h Toxicity to algae : EC50 (Selenastrum capricornutum (green algae)): 20 mg/l End point: Growth rate Exposure time: 96 h Test Type: static test Toxicity to microorganisms : EC50 (activated sludge): > 100 mg/l End point: Respiration inhibition Exposure time: 3 h Method: OECD Test Guideline 209 Test Type: static test Persistence and degradability Product: Biodegradability : Remarks: No data available ity Physico-chemical removabil- : Remarks: No data available Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Biodegradability : aerobic Inoculum: activated sludge Concentration: 100 mg/l Biodegradation: 98% Result: Readily biodegradable. Method: OECD Test Guideline 301F Exposure time: 28 d Test substance: Read-across (Analogy) GLP: yes tetrahydrofuran: Biodegradability : aerobic Inoculum: activated sludge Concentration: 100 mg/l Result: Biodegradable 21/29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 GLP: yes ethylbenzene: (COD) Chemical Oxygen Demand 1,780 mg/g Bioaccumulative potential Product: Bioaccumulation : Remarks: Bioaccumulation is unlikely. Ingredients: Naphtha (petroleum), hydrotreated light (Heptane (C7 hydrocarbon mixture)): Bioaccumulation : Remarks: No data available lithium disopropylamide: Bioaccumulation : Remarks: Bioaccumulation is unlikely. tetrahydrofuran: Bioaccumulation : Remarks: No bioaccumulation is to be expected (log Pow <= 4). Partition coefficient: n- octanol/water : log Pow: 0.45 (77 °F / 25 °C) Method: OECD Test Guideline 107 ethylbenzene: octanol/water Partition coefficient: n- : log Pow: 3.15 diisopropylamine: Partition coefficient: n- octanol/water : log Pow: 0.4 (68 °F / 20 °C) Method: OECD Test Guideline 107 pH: 12 Mobility in soil Ingredients: ethylbenzene: mental compartments Distribution among environ- : log Koc: 2.31 Remarks: The product is insoluble and floats on water. 22/29 <<>> SAFETY DATA SHEET MALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 Other adverse effects Product: Ozone-Depletion Potential : Regulation: 40 CFR Protection of Environment; Part 82 Pro- tection of Stratospheric Ozone - CAA Section 602 Class I Substances Remarks: This product neither contains, nor was manufac- tured with a Class I or Class II ODS as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App.A + B). Additional ecological infor- mation : Toxic to aquatic life with long lasting effects. Avoid subsoil penetration. Do not flush into surface water or sanitary sewer system. SECTION 13. DISPOSAL CONSIDERATIONS Disposal methods Waste from residues : Dispose of in accordance with local regulations. Contaminated packaging : Refer to manufacturer/ supplier for information on recovery/ recycling. SECTION 14. TRANSPORT INFORMATION International Regulations UN number UNRTDG Proper shipping name FLAMMA FLAMMABLE LIQUID, CORROSIVE, N.O.S. (Lithium disopropylamide, Heptane (C7 hydrocarbon mix- Subsidiary risk Class ture)) : 3 8 Packing group Labels 3(8) IATA-DGR UN/ID No. Proper shipping name Flammab Flammable liquid, corrosive, n.o.s. (Lithium diisopropylamide, Heptane (C7 hydrocarbon mix- Subsidiary risk Class ture)) 3 Labels Packing group : 8 Packing instruction (cargo Sammable Liquids, Corrosive 363 23 / 29 <<>> SAFETY DATA SHEET I ALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 1.1 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 aircraft) ger aircraft Packing instruction (passen-: 352 IMDG-Code UN number Proper shipping name FLAMMABLE LIQUID. CORROSIVE, NOS. Class (Lithium diisopropylamide, Heptane (C7 hydrocarbon mixture)) Subsidiary risk 8 3 Labels Packing group EmS Code 3 (8) F-E, S-C Marine pollutant Remarks : Alkalis yes Transport in bulk according to Annex Il of MARPOL 73178 and the IBC Code Not applicable for product as supplied. Domestic regulation 49 CFR UN/ID/NA number Proper shipping name Flammat Flammable liquids, corrosive, n.o.s. ture)) (Lithium diisopropylamide, Heptane (C7 hydrocarbon mix- Subsidiary risk Class 3 Labels Packing group 8 FLAMMABLE LIQUID, CORROSIVE ERG Code Marine pollutant :13s yes(Heptane (C7 hydrocarbon mixture)) Special precautions for user based upon the properties of the unpackaged material as it is described within this Safety Data The transport classification(s) provided herein are for informational purposes only, and solely Sheet. Transportation classifications may vary by mode of transportation, package sizes, and variations in regional or country regulations. SECTION 15. REGULATORY INFORMATION EPCRA - Emergency Planning and Community Right-to-Know CERCLA Reportable Quantity Ingredients CAS-NO. Component RQ Calculated product RQ tetrahydrofuran 109-99-9 1000 (Ibs) (Ibs) ethylbenzene 100-41-4 4347 100 100 (F003) 24/29 <<>> SAFETY DATA SHEET I ALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 12/09/2019 Print Date: SARA 304 Extremely Hazardous Substances Reportable Quantity This material does not contain any components with a section 304 EHS RQ. SARA 302 Extremely Hazardous Substances Threshold Planning Quantity This material does not contain any components with a section 302 EHS TPQ. SARA 311/312 Hazards : Flammable (gases, aerosols, liquids, or solids) Skin corrosion or irritation Carcinogenicity Serious eye damage or eye irritation Aspiration hazard Specific target organ toxicity (single or repeated exposure) SARA 313 : The following components are subject to reporting levels established by SARA Title Ill, Section 313: ethylbenzene 100-41-4 >= 10 - < 20% Clean Air Act This product neither contains, nor was manufactured with a Class I or Class II ODS as defined by The following chemical(s) are listed as HAP under the U.S. Clean Air Act, Section 12 (40 CFR 61): This product does not contain any chemicals listed under the U.S. Clean Air Act Section 112(r) for The following chemicals) are listed under the U.S. Clean Air Act Section 111 SOCMI Intermedi- Accidental Release Prevention (40 CFR 68.130, Subpart F) ethylbenzene 100-41-4 >= 10 - < 20 % Clean Water Act ble 116.4A: The following Hazardous Substances are listed under the U.S. CleanWater Act, Section 311, Ta- ethylbenzene 100-41-4 >= 10 - < 20 % The following Hazardous Chemicals are listed under the U.S. CleanWater Act, Section 311, Table ethylbenzene 100-41-4 This product contains the following toxic pollutants listed under the U.S. Clean Water Act Section >= 10 - < 20 % ethylbenzene 100-41-4 >= 10 - < 20 % US State Regulations Massachusetts Right To Know tetrahydrofuran 109-99-9 ethylbenzene diisopropylamine 100-41-4 108-18-9 Pennsylvania Right To Know Naphtha (petroleum), hydrotreated light (Heptane (C7 hydro- 64742-49-0 25 / 29 <<>> SAFETY DATA SHEET MALBEMARLE® according to OSHA Hazard Communication Standard 29CFR 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 carbon mixture)) tetrahydrofuran lithium disopropylamide 4111-54-0 109-99-9 diisopropylamine ethylbenzene 100-41-4 108-18-9 Maine Chemicals of High Concern Product does not contain any listed chemicals Vermont Chemicals of High Concern ethylbenzene 100-41-4 Washington Chemicals of High Concern ethylbenzene 100-41-4 California Prop. 65 WARNING: This product can expose you to chemicals including ethylbenzene, which is/are www.P65Warnings.ca.gov. known to the State of California to cause cancer. For more information go to California List of Hazardous Substances Naphtha (petroleum), hydrotreated light (Heptane (C7 hydro- 64742-49-0 tetrahydrofuran carbon mixture)) 109-99-9 diisopropylamine ethylbenzene 100-41-4 108-18-9 California Permissible Exposure Limits for Chemical Contaminants Naphtha (petroleum), hydrotreated light (Heptane (C7 hydro- 64742-49-0 tetrahydrofuran carbon mixture)) ethylbenzene 109-99-9 diisopropylamine 100-41-4 108-18-9 The ingredients of this product are reported in the following inventories: EINECS : On the inventory, or in compliance with the inventory DSL : All components of this product are on the Canadian DSL AICS : On the inventory, or in compliance with the inventory NZIOC : Not in compliance with the inventory ENCS : Not in compliance with the inventory ISHL : Not in compliance with the inventory KECI : Not in compliance with the inventory PICCS : On the inventory, or in compliance with the inventory 26 / 29 <<>> SAFETY DATA SHEET M ALBEMARLE® 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 IECSC :: On the inventory, or in compliance with the inventory TCSI : On the inventory, or in compliance with the inventory •TSCA : On TSCA Inventory TSCA list No substances are subject to a Significant New Use Rule. No substances are subject to TSCA 12(b) export notification requirements. SECTION 16. OTHER INFORMATION Further information NFPA 704: HMIS® IV: Flammability HEALTH * 3 3 FLAMMABILITY Health 3 Instability 3 PHYSICAL HAZARD 0 HMIS® ratings are based on a 0-4 rating ards or risks, and 4 representing signifi- scale, with 0 representing minimal haz- Special hazard. cant hazards or risks. The "* represents the absence of a chronic hazard. a chronic hazard, while the "/" represents Full text of other abbreviations ACGIH BEI ACGIH : USA. ACGIH Threshold Limit Values (TLV) NIOSH REL : ACGIH - Biological Exposure Indices (BEI) OSHA PO USA. NIOSH Recommended Exposure Limits USA. OSHA - TABLE Z-1 Limits for Air Contaminants - OSHA Z-1 : USA. Occupational Exposure Limits (OSHA) - Table Z-1 Lim 1910.1000 ACGIH / TWA its for Air Contaminants ACGIH / STEL 8-hour, time-weighted averag NIOSH REL / TWA : Short-term exposure limi Time-weighted average concentration for up to a 10-hour workday during a 40-hour workweek 27 / 29 <<>> SAFETY DATA SHEET I ALBEMARLE 1910.1200 (HCS 2012) according to OSHA Hazard Communication Standard 29CFR Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 10/09/2019 Revision Date: Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 NIOSH REL / ST : STEL - 15-minute TWA exposure that should not be exceeded OSHA PO / TWA 8-hour time weighted average at any time during a workday OSHA PO / STEL Short-term exposure limit OSHA Z-1 / TWA 8-hour time weighted average Materials; bw - Body weight; CERCLA - Comprehensive Environmental Response, Compensation, AICS - Australian Inventory of Chemical Substances; ASTM - American Society for the Testing of and Liability Act; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the stances List (Canada); ECx - Concentration associated with x% response; EHS - Extremely Haz- German Institute for Standardisation; DOT - Department of Transportation; DSL - Domestic Sub- ardous Substance; ELX - Loading rate associated with x% response; EmS - Emergency Schedule; x% growth rate response; ERG - Emergency Response Guide; GHS - Globally Harmonized Sys- ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with International Agency for Research on Cancer; IATA - International Air Transport Association; IBC tem; GLP - Good Laboratory Practice; HMIS - Hazardous Materials Identification System; IARC - - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals tion; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organiza- Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety and Health cals Inventory; LC50 - Lethal Concentration to 50% of a test population; LD50 - Lethal Dose to Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemi- 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Pre- erwise Specified; NFPA - National Fire Protection Association; NO(A)EC - No Observed (Adverse) vention of Pollution from Ships; MSHA - Mine Safety and Health Administration; n.o.s. - Not Oth- Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office Effect Loading Rate; NTP - National Toxicology Program; NZloC - New Zealand Inventory of stance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quanti- of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic sub- REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concern- Structure Activity Relationship; RCRA - Resource Conservation and Recovery Act; ing the Registration, Evaluation, Authorisation and Restriction of Chemicals; RQ - Reportable Quantity; SADT - Self-Accelerating Decomposition Temperature; SARA - Superfund Amend- ments and Reauthorization Act; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TSCA - Toxic Substances Control Act (United States); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very Bioaccumulative Revision Date : 10/09/2019 The information provided in this Material Safety Data Sheet is correct to the best of our only as a guidance for safe handling, use, processing, storage, transportation, disposal and re- knowledge, information and belief at the date of its publication. The information given is designed lease and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. 28 / 29 <<>> SAFETY DATA SHEET according to OSHA Hazard Communication Standard 29CFR I ALBEMARLE 1910.1200 (HCS 2012) Lithium Di-isoproplyamide abt. 27% in THF/ Heptane/ Ethylbenzene SDS Number: RS_000001280 Version 1.1 Revision Date: 10/09/2019 Date of last issue: 03/04/2019 Date of first issue: 03/04/2019 Print Date: 12/09/2019 US / Z8 29 / 29 ## Provenance - Official: Yes - Source: - Source ID: `phmsa` - SHA-256: `90e643f08a1d5755bb74574022bc7da6ad03626fa0f1ac1b7f2259a8ccf816c1` - Retrieved: 2026-08-20T00:59:31.977Z - Exported: 2026-08-23T14:02:39.637Z - Document slug: `phmsa-interpretation-19-0133` ### Source metadata ```json { "materialSubtype": "interpretation", "interpretationArea": "hazardous_materials", "representation": "full_text_from_official_pdf", "companies": [ "Dangerous Goods SME" ], "individuals": [ "William Canterbury" ], "refIds": [ "19-0133" ], "catalogDates": [ "2020-04-28" ], "catalogParts": [ 172 ], "catalogRowCount": 1, "sourceRecordUrls": [ "https://www.phmsa.dot.gov/node/72081" ], "linkedAttachmentUrls": [], "unavailableResponseUrls": [], "duplicateRepresentationUrls": [], "citedSections": [ "172.203", "172.203(k)", "171.8", "172.101(c)(10)" ], "catalogPageUrls": [ "https://www.phmsa.dot.gov/regulations/title49/section/172203" ], "pdfUrls": [ "https://www.phmsa.dot.gov/sites/phmsa.dot.gov/files/docs/standards-rulemaking/hazmat/interpretations/73731/190133.pdf" ], "representations": [ { "viewUrl": "https://www.phmsa.dot.gov/sites/phmsa.dot.gov/files/docs/standards-rulemaking/hazmat/interpretations/73731/190133.pdf", "detailUrl": null, "detailHtmlPath": null, "pdfUrl": "https://www.phmsa.dot.gov/sites/phmsa.dot.gov/files/docs/standards-rulemaking/hazmat/interpretations/73731/190133.pdf", "pdfArtifactPath": "data/sources/phmsa-interpretations/19-0133-a600066132.pdf", "pdfArtifactSha256": "b81aba5f0f45016e5c98d288c4622f80b9446d858fa71ab4508a53bbe9f654a4", "extractedTextPath": "data/sources/phmsa-interpretations/19-0133-a600066132.v2.txt", "extractedTextSha256": "4f41ce088646c7045fb49f2f2a68be8caffd839c8401d702e660a1d299c47299", "pageCount": 33, "extractionVersion": 2 } ], "caveat": "Interpretations apply regulations to the facts presented and do not create independently enforceable requirements.", "jurisdiction": "US" } ```