# What drugs do laboratories test for?

- **operation:** document
- **citation:** 49 CFR 40.82
- **title:** What drugs do laboratories test for?
- **source type:** regulation
- **agency:** Pipeline and Hazardous Materials Safety Administration
- **status:** current
- **official:** true
- **published on:** Not available
- **effective on:** 2026-08-18
- **summary:** As a laboratory, you must test for the following five drugs or classes of drugs in a DOT drug test. You must not test “DOT specimens” for any other drugs.

(a) Marijuana metabolites.

(b) Cocaine metabolites.

(c) Amphetamines.

(d) Opioids.

(e) Phencyclidine (PCP).

[82 FR 52244, Nov. 13, 2017. Re
- **machine formats:** - **json:** https://regulus.evalyn.ai/document/49-cfr-40-82.json
- **markdown:** https://regulus.evalyn.ai/document/49-cfr-40-82.md
- **app url:** https://regulus.evalyn.ai/document/49-cfr-40-82
- **source url:** https://www.ecfr.gov/on/2026-08-18/title-49/section-40.82
**body:**

As a laboratory, you must test for the following five drugs or classes of drugs in a DOT drug test. You must not test “DOT specimens” for any other drugs.

(a) Marijuana metabolites.

(b) Cocaine metabolites.

(c) Amphetamines.

(d) Opioids.

(e) Phencyclidine (PCP).

[82 FR 52244, Nov. 13, 2017. Redesignated at 88 FR 27643, May 2, 2023]
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- **body characters:** 339