{"operation":"document","citation":"09-0233","title":"Thermo Fisher Scientific — Hazardous Materials Safety Interpretation","source_type":"guidance","agency":"Pipeline and Hazardous Materials Safety Administration","status":"guidance","official":true,"published_on":"2009-12-15","effective_on":null,"summary":"09-0233 response to Thermo Fisher Scientific concerning 172.101, 173.22.","machine_formats":{"json":"https://regulus.evalyn.ai/document/phmsa-interpretation-09-0233.json","markdown":"https://regulus.evalyn.ai/document/phmsa-interpretation-09-0233.md"},"app_url":"https://regulus.evalyn.ai/document/phmsa-interpretation-09-0233","source_url":"https://www.phmsa.dot.gov/sites/phmsa.dot.gov/files/legacy/interpretations/Interpretations/2009/090233.pdf","body":"<<<PAGE 1>>>\n\nU.S. Department of Transportation Pipeline and Hazardous Material Safety Administration\nDEC 15 2009\n1200 New Jersey AI/e, S.E.\nWashington. D.C. 20590\nMr. Gene Sanders\nSenior Dangerous Goods Transportation Specialist\nThenno Fisher Scientific\n2000 Park Lane\nPittsburgh, PA 15275 USA\nRef. No. 09-0233\nDear Mr. Sanders:\nThis responds to your October 15, 2009 request for clarification of the Hazardous Materials\nRegulations (HMR; 49 CFR Parts 171-180). Specifically, you ask for assistance in\ndetennining the hazard class for your alcohol mixture.\nAccording to your letter, your product (Fast Orange G ; Pigment Orange 13, Pyrazolone\nOrange, C.1. 21110, CAS#3520-72-7) has a chemical structure that, according to Appendix 6\nto the United Nations Manual of Tests and Criteria, fourth revised edition, may result in\nunintended explosive or self-reactive properties. You do not have test data that indicates\nwhether this material meets the definition of a Class 1 ( explosive) or a Di vision 4.1 (selfreactive)\nmaterial. You state that the Fast Orange G is diluted to less than 1 % with common\nalcohols, water, and less than 1 % Phosphotungstic acid. You suggest that at this\nconcentration, even if pure Fast Orange G met the definition for a Class 1 (explosive)\nmaterial, it has been sufficiently desensitized that it no longer exhibits explosive\ncharacteri sties.\nSection 173.22 requires a shipper to properly class and describe a hazardous material for\ntransportation in commerce. This Office does not perfonn that function. However, based on\nthe infonnation provided in your letter and the MSDS enclosed in your letter, it is the opinion\nof this Office that your product should be described as \"UN 1993, Flammable liquid solution,\nn.o.s., 3, 11.\"\nI hope this answers your inquiry. If you need further assistance, please contact this Office.\nSincerly, .tJ\n71ft 6'124!-ib\nCharles E. Betts\nChief, Standards Development\nOffice of Hazardous Materials Standards\n\n<<<PAGE 2>>>\n\nTransport classification verification requested Page 1 of 1\nDrakeford, Carolyn (PHMSA)\nFrom: Gorsky, Susan (PHMSA)\nSent: Friday, October 16, 2009 7:41 AM\nTo: Drakeford, Carolyn (PHMSA) ~112. 101\nSubject: FW: Transport classification verification requested QJCl!)Si ~ Co.n;YI\nAttachments: Pigment Orange 13.pdf; OG-6 MSDS.pdf\nOQ-OZ3'3\nBoo+h~'\nFrom: Sanders, Gene [mailto:gene.sanders@thermofisher.com]\nSent: Thursday, October 15, 2009 5:52 PM\nTo: Gorsky, Susan (PHMSA); Gorsky, Susan (PHMSA); Watson, Spencer (PHMSA); Watson, Spencer (PHMSA)\nCc: Mayfield, John; Kosarich, Kathy\nSubject: Transport classification verification requested\nDr. Watson and Ms. Gorsky,\nFast Orange G (Pigment Orange 13, Pyrazolone Orange, C.1. 21110, CAS# 3520-72-7), chemical structure\nattached, has a chemical structure which Appendix 6 to the United Nations Manual of Tests and Criteria, fourth\nrevised edition, suggests may cause it to have some unintended explosive or self-reactive properties. No test\ndata has been found to indicate whether or not this material might meet the definition of a Class 1 or a Division\n4.1 self-reactive.\nIn a product known as OG-6, Fast Orange G is diluted to less than 1 % in some common alcohols, water,\nand less than 1% Phosphotungstic acid, MSDS attached, At this concentration, even if pure Fast Orange G were\nto be a Class 1 material, it seems reasonable to believe that it has been adequately desensitized.\nDoes PHMSA find anything non-compliant with using the following transport classifications for OG-6?\n49CFR: UN1987, Alcohols, n.o.s., 3, II\nICAO: UN1987, Alcohols, n.o.s. (Ethanol, Methanol, Isopropanol), 3, II\nIMO: UN1987, Alcohols, n.o.s. (Ethanol, Methanol, Isopropanol), 3, II\nThank you for your review and evaluation.\nCheers,\nGene Sanders, DGSA\nSenior Dangerous Goods Transportation Specialist\nThermo Fisher Scientific\n2000 Park Lane\nPittsburgh, Pa. 15275 USA\nGene.Sanders@ThermoFisher.com\n412/490-8934, cell 412/498-2458, fax 412/490-8930\nwww.thermofisher.com\nThe world leader in serving science\nWORLDWIDE CONFIDENTIALITY NOTE: Dissemination, distribution or copying of this e-mail or the information herein by anyone other than the\nintended recipient. or an employee or agent of a system responsible for delivering the message to the intended recipient, is prohibited. If you are not the\nintended recipient. please inform the sender and delete all copies.\n-_...:==;<\n«Pigment Orange 13.pdf» «OG-6 MSDS.pdf»\n10116/2009\n\n<<<PAGE 3>>>\n\nPigment Orange 13, C.I. 21110, 4,4'-[(3,3'-Dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[... Page 1 of 1\n~1!r~ Online Database of Chemicals from Around the World\n~11E!m6Iink» Chemical Listing » P» Pigment Orange 13\nPigment Orange 13\nM~ !btGoogl~\npigmeot\nCIJ!lmi.Q<lISe<lrt:hing\n$!!nivo- Cblfl.!! tlelit price\n24/7, Get real price within 0.8s Phosphoric\naCid(85%) :$667/MT (FOB)\nIron Ollide .PI.omeflt\n21 Colors, Iron Oxide Pigment. $2.10' $5.00\nper lb. free Shipping\nCb~.Q<ILf>rQj:lw:;!§\nCh!!Jl1iQ!lL~!!lQgYt;!\nAda by GooogIt\nQr.fNnjc. Qye~tllffs\nC.Q.!lL\nYour source for dyes,\npigments and\ncolorants for all\nindustries.\nwww.OrganicDye.com\nQvalityQrgani.::\n~gmen.ts\nPigments for\ninks,coatings,plastics\nCall Aceto 516-6276000\nwww.aceto.com\nfi\"~Chl,\\!!mh:;ills\nstate-of-the-art,\nmodern producer good\nprices & service,\nCheck now\nwww.jhchem.com\n~llljl!JtPeilri\nSearch Thousands of\nCatalogs for Pigment\nPearl\nwww.globalspec.com\nIdentification\nName Pigment Orange 13\nC.L 21110; 4,4'·[(3,3'·Oichloro[l,l'-biphenylj-4,4'-diyl)bis\nSynonyms (azo)]bis[2,4-dihydro·5-methyl·2·phenyl-3H-pyrazol-3-one]\nLearp A.bout Chapter 7\nFree Online Evaluation &\nChapter 7 Infonnation.\nLawyers Nationwide\n\\V, .. ,\\ T()t:llBan~nlpt~~ (lIm\nPurcb~~.e Ch~rnk!ll$ T()d~y\nRare and Unusual Chemicals\nOrganic, Inorganic & Patina\nU\"q\\ Clt,ChcmlCal com\nMolecular Structure\nMolecular Formula C3zHz4ClzNaOz\nMolecular Weight 623.49\nCAS Registry Number 3520-72·7\nEINECS 222-530-3\nR~\\jabll,\\!!(:hemk:als\nList of Suppliers\nThe CompleteList of Suppliers for Pigment OranQ.e 13\nMarket Analysis Reports\nl,.istQf Reports~l,Iailiilblefor Pigment Orange 13\ni\"~A\nMethylbenzothiazole,\nCarbazates, Diethyl\nMaleate, Hydrazides\nwww.AIDchemlcal.com\nPhlhalhydrazide Phthailc anhydride Phthallde O·Phthailmide 4-(Phthajlmlde)cyclohexanol 2·12-(2-Phthallmidoethoxy)ethoxyjacetJc aCid 2.Phthallmldo·3·methylbutanoic aCId 6(Phlhalimidomethylj.8.11-dihydro-5H-dibenz[b.elazepme\n3·Phthalimldopropionaldehyde 2·Phthallmldoproplonlc aCid 3·Phthalimldopropionlc aCid alpha-Phthalimldoproplophenone\nPhthalon;lrlle Phthaloyl amlodlplne Phthaloyl dichloride N-Phthaloylglyclne Phthalylglycyl chlonde Phthalylsulfathiazole Physclon Phytase Phytlc aCId Plberaline Plcloram 2·\nPicollne 3-Picoltne 4·Plcollne·N·oXlde 2·Plcoline·N-{)xide 3·Plcollne·N·oxide Plcolinlc aCid 2,Plcolylamlne 3·Plcolyl chlonde hydrochlonde 2-P,colyl chlonde hydrochloride Picoplalin\nPicotamide P,coxystrobin Plcramlc aCld Plcnc aCld Picroside I P,croslde II Pidoltmod Pigment Blue 1 Pigment Blue 15'2 Pigment BI~e 27 PIgment 81~e 29 Pigment Blue 61\nPigment Geen 7 Pigment Green 18 Pigment Green 36 Pigment Orange 16\nCopyright 2009 @) chemBlink. All rights reserved. Content Dis.clalmer I\"\"bout chemelink I Conll!CI\nhttp://www.chemblink.com/products/3520-72-7.htm 10/15/2009\n\n<<<PAGE 4>>>\n\nPrint Date: 8/01/08\nACC# 93611 Therl110 \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nMSDS Name:\nOG-6\nCatalog Numbers:\n75204, 75204E, 75211, 75211E, 75225\nSynonyms:\nNone Known.\nCompany Identification:\nRichard Allan Scientific\n4481 Campus Drive\nKalamazoo, MI 49008\nCompany Phone Number:\n800-522-7270\nEmergency Phone Number:\n800424-9300\nCHEMTREC Phone Number, US:\n(800) 424-9300\nCHEMTREC Phone Number, Europe:\n(202) 483-7616\n64-17-5 Ethyl alcohol\n7732-18-5 Water\n67-63-0 Isopropyl alcohol\n67-56-1 Methyl alcohol\n3520-72-7 Orange G\n12067-99-1 Phosphotungstic acid\n75-78 200-578-6 F 11\n12-14 231-791-2\n4-5 200-661-7 FXI 113667\n4-5\n200-659-6\nFT 11 23/24/25\n39/23/24/25\n<1.0\n222-530-3\n<1.0 235-087-6\nPage 1\n\n<<<PAGE 5>>>\n\nPrint Date: 8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nEMERGENCY OVERVIEW\nAppearance: Orange liquid\nDanger! Poison! Flammable liquid and vapor. May be fatal or cause blindness if\nswallowed. Harmful if swallowed, inhaled, or absorbed through the skin. Vapor\nharmful. Causes eye, skin, and respiratory tract irritation. This substance has\ncaused adverse reproductive and fetal effects in humans. May cause central nervous\nsystem depression. May cause liver, kidney and heart damage. Cannot be made\nnon-poisonous. Flash Point: 16.5°C.\nTarget Organs: Kidneys, Heart, Liver, Eyes, Nervous system, Optic nerve\nPotential Health Effects\nEye:\nCauses severe eye irritation. May cause painful sensitization to light. May cause visual impairment. May\ncause chemical conjunctivitis and corneal damage.\nSkin:\nCauses moderate skin irritation. Prolonged and/or repeated contact may cause defatting of the skin and\ndermatitis. May cause cyanosis of the extremities. Methanol can be absorbed through the skin, producing\nsystemic effects that include visual disturbances.\nIngestion:\nMay be fatal or cause blindness if swallowed. May cause gastrointestinal irritation with nausea, vomiting\nand diarrhea. May cause systemic toxicity with acidosis. May cause central nervous system depression,\ncharacterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages\nmay cause collapse, unconsciousness, coma and possible death due to respiratory failure.\nInhalation:\nInhalation of high concentrations may cause central nervous system effects characterized by nausea,\nheadache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. Methanol is toxic and\ncan very readily form extremely high vapor concentrations at room temperature. Inhalation is the most\ncommon route of occupational exposure. At first, methanol causes CNS depression with nausea,\nheadache, vomiting, dizziness and incoordination. A time period with no obvious symptoms follows\n(typically 8-24 hrs). This latent period is followed by metabolic acidosis and severe visual effects which may\ninclude reduced reactivity and/or increased sensitivity to light, blurred, doubl and/or snowy vision, and\nblindness. Depending on the severity of exposure and the promptness of treatment, survivors may recover\ncompletely or may have permanent blindness, vision disturbances and/or nervous system effects.\nChronic:\nProlonged or repeated skin contact may cause dermatitis. May cause reproductive and fetal effects.\nLaboratory experiments have resulted in mutagenic effects. Animal studies have reported the development\nof tumors. Prolonged exposure may cause liver, kidney, and heart damage. Chronic exposure may cause\neffects similar to those of acute exposure.\nEyes:\nGet medical aid immediately. In case of contact, immediately flush eyes with plenty of water for at least 15\nminutes. Get medical aid.\nPage 2\n\n<<<PAGE 6>>>\n\nPrint Date: 8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nSkin:\nIn case of contact, immediately flush skin with plenty of water for at least 15 minutes while removing\ncontaminated clothing and shoes. Get medical aid immediately. Wash clothing before reuse.\nIngestion:\nDo not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give\nanything by mouth to an unconscious person. Get medical aid.\nInhalation:\nIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give\noxygen. Get medical aid.\nNotes to Physician:\nEffects may be delayed. Treat symptomatically and supportively. Persons with skin or eye disorders or\nliver, kidney, chronic respiratory diseases, or central and peripheral nervous sytem diseases may be at\nincreased risk from exposure to this substance.\nAntidote:\nEthanol may inhibit methanol metabolism. Replace fluid and electrolytes.\n\"\n·:~~!i~~~'S·l'Ei:r~·~lghting·Nt~a'.·\"·\nGeneral Information:\nReplace fluid and electrolytes. As in any fire, wear a self-contained breathing apparatus in\npressure-demand, MSHAINIOSH (approved or equivalent), and full protective gear. Vapors may form an\nexplosive mixture with air. Vapors can travel to a source of ignition and flash back. During a fire, irritating\nand highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in\na fire. Use water spray to keep fire-exposed containers cool. Flammable liquid and vapor. Vapors are\nheavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground\nand collect in low or confined areas.\nExtinguishing Media:\nFor small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be\nineffective. For large fires, use water spray, fog or alcohol-resistant foam. Do NOT use straight streams of\nwater.\nAutoignition Temperature:\nNot available\nExplosion Limits:\nLower: 3.3 Upper: 19.0\nFlash Point:\n16.5°C (61.70°F)\nNFPA Rating:\n(estimated) Health: 2; Flammability: 3; Instability: 0\nGeneral Information:\nUse proper personal protective equipment as indicated in Section 8.\nPage 3\n\n<<<PAGE 7>>>\n\nPrint Date: 8/01/08\nACC# 93611 Therl110 \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG·6\nSpills/Leaks:\nAbsorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Use water\nspray to disperse the gas/vapor. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation.\nA vapor suppressing foam may be used to reduce vapors.\n~.9n/l.~i~~~;dlipg.~n~;'~tQl(a)g~;£~~·~;~Z>;;.;; ....•~\nHandling:\nWash thoroughly after handling. Remove contaminated clothing and wash before reuse. Ground and bond\ncontainers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact\nwith eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be\ndangerous. Keep container tightly closed. Do not ingest or inhale. Do not pressurize, cut, weld, braze,\nsolder, drill, grind, or expose empty containers to heat, sparks or open flames. Use only with adequate\nventilation. Keep away from heat, sparks and flame.\nStorage:\nKeep away from sources of ignition. Keep from contact with oxidizing materials. Store in a cool, dry,\nwell-ventilated area away from incompatible substances. Flammables-area. Do not store near\nperchlorates, peroxides, chromic acid or nitric acid.\nQ~;~r~;CQntfPJ$;.r:e~s~llfl~I·\\'fti~t~·~l~··'\nEngineering Controls:\nFacilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower.\nUse adequate general or local exhaust ventilation to keep airborne concentrations below the permissible\nexposure limits.\nExposure Limits\nChemical Name: ACGIH NIOSH OSHA\nEthyl alcohol 1000 ppm TWA 1000 ppm TWA; 1900 1000 ppm TWA; 1900\nmg/m3 TWA 3300 ppm mg/m3 TWA;\nIDLH (10% LEL)\nWater None listed None listed None listed\nIsopropyl alcohol 200 ppm TWA:400 ppm 400 ppm TWA; 980 400 ppm TWA; 980\nSTEL mg/m3 TWA 2000 ppm mg/m3TWA;\nIDLH (10% LEL)\nMethyl alcohol 200 ppm TWA;250 ppm 200 ppm TWA; 260 200 ppm TWA; 260\nSTEL;Skin - potential mg/m3 TWA 6000 ppm mg/m3 TWA;\nsignificant contribution IDLH\nto overall exposure by\nthe cutaneous route\nOrange G None listed None listed None listed\nPhosphotungstic acid 1 mg/m3 TWA (as W) 1 mg/m3 TWA (as W) None listed\n(listed under Tungsten, (listed under Tungsten,\nsoluble compounds); 3 soluble compounds)\nmg/m3 STEL (as W)\n(listed under Tungsten,\nsoluble compounds)\nOSHA Vacated PELs\nEthyl alcohol: 1000 ppm TWA; 1900 mg/m3 TWA\nIsopropyl alcohol: 400 ppm TWA; 980 mg/m3 TWA\nMethyl alcohol: 200 ppm TWA; 260 mg/m3 TWA\nPage 4\n\n<<<PAGE 8>>>\n\nPrint Date: 8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nPhosphotungstic acid 1 mg/m3 TWA (as W) (listed under Tungsten, soluble compounds)\nPersona) Protective Equipment\nEyes:\nSkin:\nClothing:\nRespirators:\nWear chemical splash goggles.\nWear appropriate protective gloves to prevent skin exposure.\nWear appropriate protective clothing to prevent skin exposure.\nA respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI 288.2 requirements or\nEuropean Standard EN 149 must be followed whenever workplace conditions warrant respirator use.\nPhysical State: Liquid\nColor: Orange\nOdor: Alcohol-like\npH: No information found\nVapor Pressure: 40 mm Hg\nVapor Density: 1.5 (air=1 )\nEvaporation Rate: 1.4 (Butyl acetate= 1 )\nViscosity: No information found\nBoiling Point: 76.1-89-4°C\nFreezing/Melting Point: No information found\nDecomposition Temperature: No information found\nSolubility in water: Soluble.\nSpecific Gravity/Density: 0.789 @ 21°C\nMolecular Formula: Solution\nMolecular Weight: No information found\nChemical Stability:\nStable under normal temperatures and pressures.\nConditions to Avoid:\nHigh temperatures, ignition sources, excess heat, oxidizers, confined spaces\nIncompatibilities with Other Materials\nStrong oxidizing agents, strong acids, acids, alkali metals, ammonia, hydrazine, peroxides, sodium, acid\nanhydrides, calcium hypochlorite, chromyl chloride, nitrosyl perchlorate, bromine pentafluoride, perchloric\nacid, silver nitrate, mercuric nitrate, potassium tert-butoxide, magnesium perchlorate, acid chlorides,\nplatinum, uranium hexafluoride, powdered aluminum, silver oxide, iodine heptafluoride, acetyl bromide,\ndisulfuryl difluoride, tetrachlorosilane + water, acetyl chloride, powdered magnesium, permanganic acid,\nruthenium (VIII) oxide, uranyl perchlorate, potassium dioxide\nPage 5\n\n<<<PAGE 9>>>\n\nACC# 93611 Print Date: 8/01/08\nThermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nHazardous Decomposition Products\nCarbon monoxide, carbon dioxide, formaldehyde\nHazardous Polymerization\nHas not been reported\nRTECS:\nCAS# 64-17-5: KQ6300000\nCAS#7732-18-5: ZC0110000\nCAS# 67-63-0: NT8050000\nCAS# 67-56-1: PC1400000\nCAS# 3520-72-7: GE4455000\nCAS# 12067-99-1: TH5650000\nPage 6\n\n<<<PAGE 10>>>\n\nPrint Date: 8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nLD50/LC50:\nCAS# 64-17-5:\nOraize test, rabbit, eye: 500 mg Severe\nOraize test, rabbit, eye: 500 mg/24H Mild\nOraize test, rabbit, skin: 20 mg/24H Moderate\nInhalation, mouse: LC50 = 39 gm/m3/4H\nInhalation, rat: LC50 = 20000 ppm/10H\nOral, mouse: L050 = 3450 mg/kg\nOral, rabbit: L050 =6300 mg/kg\nOral, rat: L050 =7060 mg/kg\nOral, rat: L050 =9000 mg/kg.\nCAS# 7732-18-5:\nOral, rat: L050 = >90 mUkg.\nCAS# 67-63-0:\nOraize test, rabbit, eye: 100 mg Severe\nOraize test, rabbit, eye: 10 mg Moderate\nOraize test, rabbit, eye: 100 mg/24H Moderate\nOraize test, rabbit, skin: 500 mg Mild\nInhalation, mouse: LC50 =53000 mg/m3\nInhalation, rat: LC50 = 16000 ppm/8H\nInhalation, rat: LC50 =72600 mg/m3\nOral, mouse: L050 = 3600 mg/kg\nOral, mouse: L050 = 3600 mg/kg\nOral, rabbit: L050 =6410 mg/kg\nOral, rat: L050 = 5045 mg/kg\nOral, rat: L050 = 5000 mg/kg\nSkin, rabbit: L050 = 12800 mg/kg.\nCAS# 67-56-1 :\nOraize test, rabbit, eye: 40 mg Moderate\nOraize test, rabbit, eye: 100 mg/24H Moderate\nOraize test, rabbit, skin: 20 mg/24H Moderate\nInhalation, rabbit: LC50 = 81000 mg/m3/14H\nInhalation, rat: LC50 =64000 ppm/4H\nOral, mouse: L050 = 7300 mg/kg\nOral, rabbit: L050 = 14200 mg/kg\nOral, rat: L050 = 5600 mg/kg\nSkin, rabbit: LD50 = 15800 mg/kg.\nCAS# 3520-72-7:\nOral, rat: L050 = >5 gm/kg.\nCAS# 12067-99-1 :\nOral, rat: L050 =3300 mg/kg.\nCarcinogenicity:\nCAS# 64-17-5\nACGIH: Not listed\nCalifornia: Not listed\nNTP: Not listed\nfARC: Group 1 carcinogen\nCAS# 7732-18-5: Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.\nCAS# 67-63-0: Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.\nCAS# 67-56-1: Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.\nCAS# 3520-72-7: Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.\nCAS# 12067-99-1: Not listed as a carcinogen by ACGIH, IARC, NTP, or CA Prop 65.\nPage 7\n\n<<<PAGE 11>>>\n\nPrint Date: 8/01/08\nACC# 93611 Therl110 \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nEpidemiology:\nEthanol has been shown to produce fetotoxicity in the embryo or fetus of laboratory animals. Prenatal\nexposure to ethanol is associated with a distinct pattern of congenital malformations that have collectively\nbeen termed the \"fetal alcohol syndrome\".\nTeratogenicity :\nThere is no human information available. Methanol is considered to be a potential developmental hazard\nbased on animal data. In animal experiments, methanol has caused fetotoxic or teratogenic effects without\nmaternal toxicity.\nReproductive:\nSee actual entry in RTECS for complete information.\nMutagenicity:\nSee actual entry in RTECS for complete information.\nNeurotoxiCity:\nNo information found\nOther:\nStandard Draize Test(Skin, rabbit) = 20 mg124H (Moderate) Standard Draize Test: Administration into the\neye (rabbit) = 500 mg (Severe).\n:?~~~i~l#c;l~ ~~co:I()gical InfQfiliatf9~~~~['\nEcotoxicity:\nFish: Fathead Minnow: 29.4 gIL; 96 Hr; LCSO (unspecified)\nFish: Goldfish: 250 ppm; 11 Hr; resulted in death\nFish: Rainbow trout: 8000 mg/L; 48 Hr; LCSO (unspecified)\nFish: RainbOW trout: LCSO =13-68 mg/L; 96 Hr.; 12 degrees C\nFish: Fathead Minnow: LCSO = 29400 mg/L; 96 Hr.; 25 degrees C, pH 7.63\nFish: Rainbow trout: LCSO =8000 mglL; 48 Hr.; Unspecified\nBacteria: Phytobacterium phosphoreum: ECSO =51,000-320,000 mg/L; 30 minutes; Microtox test\nFish: Rainbow trout: LCSO = 12900-15300 mg/L; 96 Hr; Flow-through @ 24-24.3°C\nFish: Rainbow trout: LCSO =11200 mg/L; 24 Hr; Fingerling (Unspecified)\nBacteria: Phytobacterium phosphoreum: ECSO = 34900 mg/L; 5-30 min; Microtox test\nWhen spilled on land it is apt to volatilize, biodegrade, and leach into the ground water, but no data on the\nrates of these processes could be found. Its fate in ground water is unknown. When released into water it\nwill volatilize and probably biodegrade. It would not be expected to adsorb to\nsediment or bioconcentrate in fish.\nEnvironmental:\nWhen released to the atmosphere it will photodegrade in hours\n(polluted urban atmosphere) to an estimated range of 4 to 6 days in less polluted areas. Rainout should be\nsignificant.\nPhysical:\nNo information found\nOther:\nNo information found\nPage 8\n\n<<<PAGE 12>>>\n\nPrint Date: ~8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nChemical waste generators must determine whether a discarded chemical is classified as a hazardous\nwaste. US EPA guidelines for the classification determination are listed in 40 CFR Part 261.3. Additionally,\nwaste generators must consult state and local hazardous waste regulations to ensure complete and\naccurate classification.\nRCRA P Series Wastes\nNone of the components are on this list.\nRCRA U Series Wastes\nCAS# 67-56-1: waste number U154 (Ignitable waste).\nUSOOT\nProper Shipping ALCOHOLS,\nName:\nN.O.S.\nHazard Class: 3\nUN Number: UN1987\nPacking Group: II\nUSA RQ: CAS# 67-56-1: 5000 Ib final RQ; 2270 kg final RQ\nCanadian TOG\nALCOHOLS,\nN.O.S.\n3\nUN1987\nII\nUS Federal\nTSCA\nCAS# 64-17-5 is listed on the TSCA Inventory.\nCAS# 7732-18-5 is listed on the TSCA Inventory.\nCAS# 67-63-0 is listed on the TSCA Inventory.\nCAS# 67-56-1 is listed on the TSCA Inventory.\nCAS# 3520-72-7 is listed on the TSCA Inventory.\nCAS# 12067-99-1 is listed on the TSCA Inventory.\nHealth and Safety Reporting List\nCAS# 67-63-0: Effective 12/15/86, Sunset 12/15/96\nChemical Test Rules\nCAS# 67-63-0: 40 CFR 799.2325\nTSCA Section 12b\nNone of the components are on this list.\nTSCA Significant New Use Rule (SNUR)\nNone of the components are on this list.\nCERCLA Hazardous Substances and corresponding RQs\nCAS# 67-56-1: 5000 Ib final RQ; 2270 kg final RQ\nPage 9\n\n<<<PAGE 13>>>\n\nPrint Date: 8/01/08\nACC# 93611 Thermo \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nSARA Section 302 Extremely Hazardous Substances\nNone of the components are on this list.\nSARA Hazard Categories\nCAS# 64-17 -5: immediate, delayed, fire.\nCAS# 67-63-0: immediate, delayed, fire.\nCAS# 67-56-1: immediate, fire.\nCAS# 12067-99-1: immediate, fire.\nSARA Section 313\nThis material contains Isopropyl alcohol {CAS# 67-63-0, 4-5%}, which is subject to the reporting\nrequirements of Section 313 of SARA Title III and 40 CFR Part 372.\nThis material contains Methyl alcohol (CAS# 67-56-1, 4-5%), which is subject to the reporting\nrequirements of Section 313 of SARA Title III and 40 CFR Part 372.\nClean Air Act - Hazardous Air Pollutants (HAPs)\nCAS# 67-56-1 is listed as a hazardous air pollutant (HAP).\nClean Air Act - Class 1 Ozone Depletors\nNone of the components are on this list.\nClean Air Act - Class 2 Ozone Depletors\nNone of the components are on this list.\nClean Water Act - Hazardous Substances\nNone of the components are on this list.\nClean Water Act - Priority Pollutants\nNone of the components are on this list.\nClean Water Act - Toxic Pollutants\nNone of the components are on this list.\nOSHA - Highly Hazardous\nNone of the components are on this list.\nOSHA· Specifically Regulated Chemicals\nNone of the components are on this list.\nUS State\nState Right to Know\nEthyl alcohol can be found on the following state Right-to-Know lists: California, New Jersey, Pennsylvania,\nMinnesota, Massachusetts.\nIsopropyl alcohol can be found on the following state Right-to-Know lists: California, New Jersey,\nPennsylvania, Minnesota, Massachusetts.\nMethyl alcohol can be found on the following state Right-to-Know lists: California, New Jersey,\nPennsylvania, Minnesota, Massachusetts.\nNo information found\nCalifornia Prop 65\nNone of the components are on this list.\nCalifornia No Significant Risk Level\nNone of the components are on this list.\nNone of the components are on this list.\nNone of the components are on this list.\nNone of the components are on this list.\nNone of the components are on this list.\nNone of the components are on this list.\nPage 10\n\n<<<PAGE 14>>>\n\nThermo\nPrint Date: 8/01/08\nACC# 93611 Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMaterial Safety Data Sheet\nOG-6\nEuropeanlInternational Regulations\nEuropean Labelling in Accordance with EC Directives:\nHazard Symbols: F XN\nRisk Phrases: R 11 Highly flammable.\nR 20/21/22 Harmful by inhalation, in contact with skin and if swallowed.\nR 68/20/21/22 Harmful: possible risk of irreversible effects through inhalation, in contact with skin and if\nswallowed.\nSafety Phrases: S 7 Keep container tightly closed.\nS 9 Keep container in a well-ventilated place.\nS 16 Keep away from sources of ignition No smoking.\nS 33 Take precautionary measures against static discharges.\nS 36/37 Wear suitable protective clothing and gloves.\nS 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where\npossible).\nWGK (Water Danger/Protection)\nNo information found\nUnited Kingdom Occupational Exposure Limits\nNo information found\nUnited Kingdom Maximum Exposure Limits\nNo information found\nCanadian DSUNDSL\nCAS# 64-17-5 is listed on Canada's DSL List.\nCAS# 7732-18-5 is listed on Canada's DSL List.\nCAS# 67-63-0 is listed on Canada's DSL List.\nCAS# 67-56-1 is listed on Canada's DSL List.\nCAS# 3520-72-7 is listed on Canada's DSL List.\nCAS# 12067-99-1 is listed on Canada's DSL List.\nCanadian WHMIS Classifications\nThis product has a WHMIS classification of B2, D2A, D1 B, D2B.\nThis product has been classified in accordance with the hazard criteria of the Controlled Products\nRegulations and the MSDS contains all of the information required by those regulations.\nCanadian Ingredient Disclosure List\nCAS# 64-17-5 is listed on the Canadian Ingredient Disclosure List.\nCAS# 67-63-0 is listed on the Canadian Ingredient Disclosure List.\nCAS# 67-56-1 is listed on the Canadian Ingredient Disclosure List.\nCAS# 12067-99-1 is not listed on the Canadian Ingredient Disclosure List.\niti)Il;i.(i·i.f.()tller'Infg\"qfati~ij),;;\nNo information found\nMSDS Creation Date: July 21, 2005\nRevision Date: August 1, 2008\nPage 11\n\n<<<PAGE 15>>>\n\nACC# 93611 Print Date: 8/01/08\nTherl110 \n Revision Date: 8/01/2008\nSCIENTIFIC Version: 2\nMateria I Safety Data Sheet\nOG-6\nThis MSDS is intended for review and guidance in the receipt, storage, handling, use and disposal of product purchased from\nus, and for no other purpose. Use this product only as directed and in accordance with applicable instructions and warnings\nprovided with the product. Please consult your institution's policies regarding use of this product. Ifyou have obtained this\nMSDS other than in connection with the supply of this product from us, this MSDS should be consulted for general\ninformation only, and should not be relied upon for any purpose. As with the use of all hazardous materials, you should in all\ninstances follow the guidance of the MSDS provided or available with the specific product purchased.\nPage 12","truncated":false,"body_characters":28892}