# EMD Electronics — Hazardous Materials Safety Interpretation

- **operation:** document
- **citation:** 25-0083
- **title:** EMD Electronics — Hazardous Materials Safety Interpretation
- **source type:** guidance
- **agency:** Pipeline and Hazardous Materials Safety Administration
- **status:** guidance
- **official:** true
- **published on:** 2026-01-07
- **effective on:** Not available
- **summary:** 25-0083 response to EMD Electronics concerning 172.101, 173.22.
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- **app url:** https://regulus.evalyn.ai/document/phmsa-interpretation-25-0083
- **source url:** https://www.phmsa.dot.gov/sites/phmsa.dot.gov/files/2026-01/250083.pdf
**body:**

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1200 New Jersey Avenue, SE
Washington, DC 20590
U.S. Department
of Transportation
Pipeline and Hazardous
Materials Safety
Administration
January 7, 2026
Jeanne Enaux
Head of Product Compliance US
EMD Electronics
116 Fairfield Road
Princeton, NJ 08540
Reference No. 25-0083
Dear Ms. Enaux:
This letter is in response to your June 23, 2025 email requesting clarification of the Hazardous
Materials Regulations (HMR; 49 CFR Parts 171-180) applicable to the term “surfactant” with
respect to the use of “UN2927, Toxic liquid, corrosive, organic, n.o.s.” for solutions containing
tetramethylammonium hydroxide (TMAH). You ask whether a surfactant includes all substances
that can potentially accelerate dermal uptake, or if the term refers only to substances that have
hydrophobic-hydrophilic capability.
For the purposes of classifying a non-aqueous solution of TMAH, the HMR does not define the
term “surfactant.” However, the term generally refers to amphiphilic substances (containing
both hydrophobic and hydrophilic parts), which reduce surface tension in liquids, and not the
substances’ potential to accelerate dermal uptake. In accordance with § 173.22 of the HMR, it is
the shipper’s responsibility to properly classify a hazardous material. Note that if a mixture
contains a substance that can potentially accelerate dermal uptake, the shipper must use the
classification criteria of the HMR to classify the mixture and then select a proper shipping name
(e.g., UN2927, Toxic liquid, corrosive, organic, n.o.s.) in accordance with § 172.101(c)(10).
I hope this information is helpful. Please contact us if we can be of further assistance.
Sincerely,
Dirk DerKinderen
Chief, Standards Development Branch
Standards and Rulemaking Division

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25-0083
Casey
From: Jeanne Enaux <jeanne.enaux@emdgroup.com>
Sent: Monday, June 23, 2025 11:40 AM
To: INFOCNTR (PHMSA) <INFOCNTR.INFOCNTR@dot.gov>
Subject: LETTER OF INTERPRETATION REQUEST
Good morning,
We have an inquiry regarding the DG classification law and would appreciate your assistance
in clarifying its requirements.
Beginning of 2025 updated regulations for the transport of dangerous goods (IATA/IMDG) has
been published and the implemented updates include a change in classification for TMAH
(Tetramethylammonium hydroxide) and its solutions.
The recognized toxicity of TMAH is going to be introduced for all existing proper shipping
names along with the limitation to aqueous solutions. Additionally, a new proper shipping
name (UN 3560) for aqueous solutions with >25% TMAH and classification criteria for other
(non-aqueous) TMAH solutions are going to be introduced.
We have a question about the non-aqueous solution. It is mentioned in the text
Other formulation containing a surfactant > 1% and ≥ 8.75% TMAH à UN2927, toxic
liquid, corrosive, PG I
Other formulation containing a surfactant > 1% and > 2.38% - < 8.75% TMAH à
UN2927, toxic liquid, corrosive, PG II

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We would like to get a letter of interpretation on the definition of the term “surfactant” in
UN2927 classification?
(Is it only substances that have hydrophobic-hydrophilic capability OR all substances that can
potentially accelerate dermal uptake? Any other way the term should be defined?...)
Thank you in advance for your help
Regards
Jeanne Enaux
Head of Product Compliance US
Email: Jeanne.enaux@emdgroup.com
Post mail: 116 Fairfield Road, 08540 Princeton NJ, USA
Tel: +18483130986
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